Thread:Josephyr/@comment-31423430-20160107001259/@comment-5811199-20160107002421

If you are an admin of a wiki, yes you can absolutely delete the specific reply. For example, this reply is housed on the page Thread:Josephyr/@comment-Homer77-20160107001259/@comment-Noreplyz-20160107002421 and can be deleted by deleting that page.

The other option is to 'hide' it by hitting the 'Remove' button. It will hide it, but people can occasionally still view the post.